Description

n-Propyl 2,3-Difluoro-6-Nitroaniline is a specialized fluorinated aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both nitro and difluoro substituents on an aniline core, makes it a valuable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Building block for developing next-generation herbicides and pesticides with enhanced efficacy and environmental profile.
• Material Science Research: Used in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro group and fluorine atoms.
• Dye and Pigment Intermediate: Serves in the synthesis of advanced colorants and fluorophores for analytical and imaging applications.
• Cross-Coupling Reactions: Aniline nitrogen and halogen sites facilitate use in Buchwald-Hartwig amination and other palladium-catalyzed transformations.

Basic Information

Product Name	n-Propyl 2,3-Difluoro-6-Nitroaniline
CAS No.	1250052-21-1
Molecular Formula	C9H10F2N2O2
Molecular Weight	216.19 g/mol
Synonyms	2,3-Difluoro-6-nitro-N-propylaniline; 1-(2,3-Difluoro-6-nitrophenyl)propylamine; N-Propyl-2,3-difluoro-6-nitrobenzenamine; 2,3-Difluoro-6-nitro-N-propylbenzenamine; Benzenamine, 2,3-difluoro-6-nitro-N-propyl-; N-Propyl-2,3-difluoro-6-nitroaniline
EINECS	Contact for details

Quality Control

Every batch of n-Propyl 2,3-Difluoro-6-Nitroaniline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports compliance in regulated development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.