Description

1-(3-Fluorophenyl)But-3-En-1-Amine is a versatile fluorinated aromatic amine building block with a reactive terminal alkene group. This unique bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Polymer & Material Science: The amine and alkene functionalities allow for incorporation into specialty polymers, dendrimers, or as a surface modification agent.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or affinity probes for studying biological systems and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1-(3-Fluorophenyl)But-3-En-1-Amine
CAS No.	1250043-70-9
Molecular Formula	C10H12FN
Molecular Weight	165.21 g/mol
Synonyms	3-Fluoro-β-vinylbenzeneethanamine; 1-(3-Fluorophenyl)-3-buten-1-amine; 3-Fluorobenzeneethanamine, β-ethenyl-; But-3-en-1-amine, 1-(3-fluorophenyl)-; 3-Fluoro-β-vinylphenethylamine; (3-Fluorophenyl)but-3-en-1-amine; 4-Amino-1-(3-fluorophenyl)but-1-ene
EINECS	Contact for details

Quality Control

Every batch of 1-(3-Fluorophenyl)But-3-En-1-Amine is produced and tested under strict quality management protocols. We ensure identity, purity, and consistency through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing all relevant specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.