Description

4-(3-Chloro-4-Fluorophenyl)Pyrimidin-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated pyrimidine structure. This compound is of significant commercial value for its role as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and other complex organic molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-performance materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive pyrimidine core.
• Chemical Synthesis: Serves as a versatile building block for constructing more complex heterocyclic compounds in organic chemistry.
• Material Science: Potential application in the development of organic electronic materials and ligands for catalysis.
• Biochemical Research: Utilized as a standard or reagent in biochemical assays and proteomics research.

Basic Information

Product Name	4-(3-Chloro-4-Fluorophenyl)Pyrimidin-2-Amine
CAS No.	1249713-59-4
Molecular Formula	C10H7ClFN3
Molecular Weight	223.63 g/mol
Synonyms	2-Amino-4-(3-chloro-4-fluorophenyl)pyrimidine; 4-(3-Chloro-4-fluorophenyl)-2-pyrimidinamine; 1249713-59-4; 4-(3-Chloro-4-fluoro-phenyl)-pyrimidin-2-ylamine; 2-Pyrimidinamine, 4-(3-chloro-4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 4-(3-Chloro-4-Fluorophenyl)Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.