Description

1-(4-Bromo-3-Fluorophenyl)Cyclopropan-1-Ol is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclopropanol-substituted aromatic ring system. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and agrochemical industries for developing new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery programs.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides, leveraging the bioactivity of the fluorinated phenyl ring.
• Ligand & Catalyst Development: Serves as a sophisticated scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers for advanced functional materials.
• Chemical Biology Probes: Utilized as a core structure for developing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	1-(4-Bromo-3-Fluorophenyl)Cyclopropan-1-Ol
CAS No.	1247191-31-6
Molecular Formula	C9H8BrFO
Molecular Weight	231.06 g/mol
Synonyms	1-(4-Bromo-3-fluorophenyl)cyclopropanol; 1-(4-Bromo-3-fluorophenyl)cyclopropan-1-ol; 4-Bromo-3-fluoro-α-(cyclopropyl)benzenemethanol; (4-Bromo-3-fluorophenyl)cyclopropylmethanol; Cyclopropanol, 1-(4-bromo-3-fluorophenyl)-; 1247191-31-6; 1-(4-Bromo-3-fluoro-phenyl)-cyclopropan-1-ol
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-3-Fluorophenyl)Cyclopropan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.