Description

[1-(2-Chloro-6-Methyl-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Methanol is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine-pyrimidine hybrid structure. This compound is of significant commercial value for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for use in synthesis and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization to create libraries of compounds for high-throughput screening.
• Academic & Contract Research: Employed in university and CRO settings for medicinal chemistry projects and structure-activity relationship (SAR) studies.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial manufacturing of complex molecules.

Basic Information

Product Name	[1-(2-Chloro-6-Methyl-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Methanol
CAS No.	1247103-30-5
Molecular Formula	C11H16ClN3O
Molecular Weight	241.72 g/mol
Synonyms	4-Piperidinemethanol, 1-(2-chloro-6-methyl-4-pyrimidinyl)-; (1-(2-Chloro-6-methylpyrimidin-4-yl)piperidin-4-yl)methanol; 1-(2-Chloro-6-methylpyrimidin-4-yl)piperidine-4-methanol; 1247103-30-5; 4-((1-(2-Chloro-6-methylpyrimidin-4-yl)piperidin-4-yl)methanol); 1-(2-Chloro-6-methyl-4-pyrimidinyl)-4-piperidinemethanol
EINECS	Contact for details

Quality Control

Our production of [1-(2-Chloro-6-Methyl-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Methanol adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified via modern analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.