Description

2-(Pentafluorothio)Aniline, also known as 2-(Pentafluorosulphanyl)Aniline, is a specialized aromatic amine building block distinguished by the unique pentafluorosulfanyl (SF5) functional group. This compound matters for its role as a critical intermediate in advanced material science and pharmaceutical research, where the SF5 group is prized for imparting high thermal stability, lipophilicity, and electron-withdrawing properties. It is primarily needed by R&D chemists and process development scientists in agrochemical, pharmaceutical, and specialty polymer industries for synthesizing novel active ingredients and high-performance materials.

Application

• Agrochemical Intermediate: Key precursor for developing novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profile.
• Pharmaceutical Research: Building block for creating potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Liquid Crystal & OLED Materials: Used in the synthesis of advanced electronic materials for displays and optoelectronic devices due to the SF5 group's influence on molecular polarity and stability.
• Polymer & Resin Modification: Serves as a monomer or cross-linking agent to introduce fluorine-containing moieties, improving chemical resistance and thermal properties of specialty polymers.
• Ligand Synthesis for Catalysis: Employed in the preparation of novel ligands for transition metal catalysts used in asymmetric synthesis.
• Fluorinated Dye & Pigment Production: Intermediate for creating dyes and pigments with superior lightfastness and chemical stability.

Basic Information

Item	Detail
Product Name	2-(Pentafluorothio)Aniline, 2-(Pentafluorosulphanyl)Aniline
CAS No.	1246998-10-6
Molecular Formula	C6H4F5NS
Molecular Weight	217.16 g/mol
Synonyms	2-Aminophenylsulfur pentafluoride; 2-SF5-Aniline; 2-(Pentafluorosulfanyl)benzenamine; 2-(SF5)C6H4NH2; o-Pentafluorosulfanylaniline; 2-(Pentafluorothio)phenylamine; 2-(Pentafluorosulfuranyl)aniline; 1-Amino-2-(pentafluorosulfanyl)benzene
EINECS	Contact for details

Quality Control

Our 2-(Pentafluorothio)Aniline undergoes rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced techniques like HPLC, GC, NMR, and elemental analysis to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to a cGMP-compliant quality management system to ensure batch-to-batch consistency and traceability for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature (store away from light), the container should be opaque or stored in dark conditions. For long-term storage, consider under an inert atmosphere to maintain purity.

Specification

Item	Specification
Appearance	Light yellow to amber liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.