Description

Fmoc-R(Pbf)Pnhet CAS NO 1246940-88-4 is a specialized, high-purity protected amino acid derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over side-chain reactivity during solid-phase peptide assembly. It is an essential building block for the development of novel therapeutic peptides, diagnostic agents, and biochemical tools within the pharmaceutical and biotechnology sectors.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the sequential construction of complex peptide chains.
• Pharmaceutical Research & Development: For the synthesis of peptide-based drug candidates, including hormone analogs and enzyme inhibitors.
• Combinatorial Chemistry Libraries: Used to generate diverse arrays of peptide compounds for high-throughput screening against biological targets.
• Bioconjugation: Serves as a precursor for creating peptide-protein or peptide-small molecule conjugates for targeted therapies.
• Academic & Industrial Research: A fundamental reagent in laboratories studying protein structure-function relationships and peptide chemistry.
• Production of Custom Peptides: Essential for CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) offering bespoke peptide synthesis services.

Basic Information

Product Name	Fmoc-R(Pbf)Pnhet
CAS No.	1246940-88-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fmoc-Arg(Pbf)-OH; Fmoc-NG-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)arginine; N-α-Fmoc-Nω-Pbf-L-arginine; Fmoc-L-Arg(Pbf)-OH; Fmoc-Arg(Pbf); NG-(2,2,4,6,7-Pentamethyldihydrobenzofuran-5-sulfonyl)-Nα-(9-fluorenylmethoxycarbonyl)-L-arginine; Fmoc-Arginine(Pbf)-OH; Fmoc-Arg(Pbf)-OH, Fmoc protected arginine derivative
EINECS	Contact for details

Quality Control

Our Fmoc-R(Pbf)Pnhet is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.