Description

4-(Trifluoromethoxy)Aniline is a high-value aromatic amine building block featuring a trifluoromethoxy substituent. This compound is essential for introducing the unique physicochemical properties of the trifluoromethoxy group into advanced molecular architectures, enhancing lipophilicity and metabolic stability. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group improves biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into polymer chains to alter thermal stability, chemical resistance, and surface properties of high-performance materials.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized dyes and pigments with enhanced color fastness and solubility properties.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in medicinal chemistry, material science, and fluorine chemistry.

Basic Information

Product Name	4-(Trifluoromethoxy)Aniline
CAS No.	1246815-55-3
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	4-Aminophenyl trifluoromethyl ether; 1-Amino-4-(trifluoromethoxy)benzene; p-(Trifluoromethoxy)aniline; 4-Trifluoromethoxyaniline; 4-(Trifluoromethoxy)benzenamine; Aniline, 4-(trifluoromethoxy)-; OC(OCC(F)(F)F)C1=CC=C(N)C=C1
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.