Description

2-(1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydrothieno[2,3-D]Pyrimidin-5-Yl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within oncology and antiviral research pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug molecules and investigational new drugs (INDs).
• API Synthesis: Serves as a core scaffold for constructing complex active pharmaceutical ingredients with specific biological activity.
• Medicinal Chemistry Research: Used in research and development (R&D) for structure-activity relationship (SAR) studies and lead optimization.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Bioconjugation: The acetic acid moiety allows for potential conjugation to carriers, antibodies, or other molecules in targeted drug delivery systems.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-(1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydrothieno[2,3-D]Pyrimidin-5-Yl)Acetic Acid
CAS No.	1246761-51-2
Molecular Formula	C10H10N2O4S
Molecular Weight	254.26 g/mol
Synonyms	5-Carboxymethyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine; 1,3-Dimethyl-2,4-dioxo-5-(carboxymethyl)-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidine-5-acetic acid, 1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-; 2-(1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-5-yl)ethanoic acid; CAS 1246761-51-2
EINECS	Contact for details

Quality Control

Our 2-(1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydrothieno[2,3-D]Pyrimidin-5-Yl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.