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n-(2'-(R)-Hydroxynervonoyl)-D-Erythro-Sphingosine CAS NO 1246298-50-9
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CAS No.:1246298-50-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-(2'-(R)-Hydroxynervonoyl)-D-Erythro-Sphingosine is a high-purity, synthetic sphingolipid derivative, a critical building block for advanced lipid research and pharmaceutical development. This compound matters as a key intermediate for synthesizing complex glycosphingolipids and for studying cell signaling, membrane biology, and apoptosis pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require well-defined, high-quality lipid standards and intermediates for drug discovery and diagnostic applications.
Application
- Biomedical Research: As a crucial standard and precursor for investigating sphingolipid metabolism, cell signaling cascades, and the role of ceramides in cellular processes.
- Pharmaceutical Intermediates: Serves as a key synthetic building block in the development of novel therapeutic agents targeting cancer, neurodegenerative diseases, and inflammatory disorders.
- Lipidomics & Analytical Standards: Used as a certified reference material in mass spectrometry and chromatography for accurate quantification and identification of sphingolipids in biological samples.
- Cosmeceutical R&D: Employed in research for developing advanced skincare formulations that target skin barrier function and cellular repair mechanisms.
- Biochemical Reagent: Utilized in enzymatic studies and as a substrate for synthesizing more complex glycosphingolipids in vitro.
- Cell Culture & Media Supplements: Incorporated into specialized cell culture media to study lipid-mediated effects on cell growth, differentiation, and viability.
Basic Information
| Item | Details |
|---|---|
| Product Name | n-(2'-(R)-Hydroxynervonoyl)-D-Erythro-Sphingosine |
| CAS No. | 1246298-50-9 |
| Molecular Formula | C40H75NO4 |
| Molecular Weight | 634.04 g/mol |
| Synonyms | (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol 1-(2'-R-Hydroxynervonoate); D-erythro-Sphingosine, N-[(2R)-2-hydroxy-15-tetracosenoyl]-; Ceramide (d18:1/2'OH-24:1(15Z)); N-(2'-Hydroxynervonoyl)-D-erythro-sphingosine; Hydroxynervonoyl Sphingosine; Sphingolipid Ceramide Analog; Synthetic Sphingosine Derivative; Lipid Research Standard |
| EINECS | Contact for details |
Quality Control
Our n-(2'-(R)-Hydroxynervonoyl)-D-Erythro-Sphingosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with the standards required for research and pharmaceutical-grade materials.
Storage
Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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