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1-Stearoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine (Sodium Salt) CAS NO 1246298-16-7


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CAS No.:1246298-16-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Stearoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine (Sodium Salt) is a high-purity, synthetic lysophospholipid of significant interest in advanced biochemical and pharmaceutical research. This compound serves as a critical precursor and model system for studying membrane biophysics, lipid signaling pathways, and the formulation of lipid-based drug delivery vehicles. It is essential for researchers and developers in the fields of liposome technology, cell biology, and advanced drug delivery systems, where precise lipid composition is paramount for replicating biological membranes or creating targeted nanocarriers.

Application

  • Liposome & Nanoparticle Formulation: A key component for creating stable, functionalized liposomes used in drug delivery, diagnostic imaging, and vaccine development.
  • Biochemical Research: Employed as a standard or substrate in enzymatic assays and studies of phospholipase activity, lipid metabolism, and intracellular signaling.
  • Cell Membrane Studies: Used to create model membrane systems (e.g., vesicles, monolayers) for investigating lipid-protein interactions, membrane fluidity, and fusion processes.
  • Pharmaceutical Excipient: Potential use as a biocompatible excipient or active targeting moiety in advanced therapeutic formulations.
  • Cosmetic Actives: Incorporated into high-end cosmetic formulations for its biomimetic properties, aiding in skin barrier repair and active ingredient delivery.
  • Diagnostic Reagent Manufacturing: Serves as a critical raw material in the production of diagnostic kits and reagents that involve lipid-based detection systems.

Basic Information

Product Name 1-Stearoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine (Sodium Salt)
CAS No. 1246298-16-7
Molecular Formula C24H47NNaO9P
Molecular Weight 547.60 g/mol
Synonyms 18:0 LysoPS (Sodium Salt); 1-Stearoyl-2-hydroxy-sn-glycero-3-phosphoserine (Sodium Salt); LysoPS(18:0/0:0) (Sodium Salt); Lysophosphatidylserine (18:0); (2R)-2-Hydroxy-3-[(1-oxooctadecyl)oxy]propyl (2S)-2-amino-3-phosphonooxypropanoate (Sodium Salt); 1-Octadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (Sodium Salt); Sodium 1-stearoyl-2-hydroxy-sn-glycero-3-phospho-L-serinate
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Quality Control

Every batch of our 1-Stearoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine (Sodium Salt) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We adhere to stringent internal quality standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (NMR, MS), and impurity profiles is provided with each shipment to support your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (NMR) Conforms to structure
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 3.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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