Description

4-(2,2-Difluoroethoxy)-2-Methoxyaniline is a specialized aromatic amine derivative featuring a difluoroethoxy substituent. This compound is a high-value intermediate of significant interest in advanced organic synthesis, particularly for constructing complex molecules with tailored properties. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluoroethoxy group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, including components for liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its aromatic amine core and fluorine content.
• Polymer Modification: Employed as a functional monomer or cross-linking agent to introduce specific amine and ether functionalities into specialty polymers, improving thermal or chemical resistance.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing complex dyes and organic pigments, where its structure contributes to color fastness and unique chromatic properties.
• Research Chemical: Supplied to academic and industrial R&D laboratories for methodological studies in fluorination chemistry and the development of new synthetic pathways.

Basic Information

Product Name	4-(2,2-Difluoroethoxy)-2-Methoxyaniline
CAS No.	1245823-81-7
Molecular Formula	C9H11F2NO2
Molecular Weight	203.19 g/mol
Synonyms	2-Methoxy-4-(2,2-difluoroethoxy)aniline; 4-(2,2-Difluoroethoxy)-2-methoxybenzenamine; 2-Methoxy-4-(2,2-difluoroethoxy)phenylamine; 2-Methoxy-4-(2,2-difluoroethoxy)aniline; Aniline, 4-(2,2-difluoroethoxy)-2-methoxy-; 1245823-81-7; DFEMA
EINECS	Contact for details

Quality Control

Our 4-(2,2-Difluoroethoxy)-2-Methoxyaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.