Description

3-Fluoro-4-[(1-Methyl-1H-Pyrazol-5-Yl)Methoxy]Aniline is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining an aniline core with a fluorinated methoxy-linked pyrazole moiety. This compound matters as a critical building block for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new drug candidates, particularly in kinase inhibitor and other targeted therapy programs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in oncology and CNS therapeutic areas.
• Kinase Inhibitor Precursor: Serves as a core structural component in the synthesis of potential kinase inhibitors due to its privileged heterocyclic architecture.
• Agrochemical Research: Used in the discovery and development of new generation herbicides and fungicides, leveraging its fluorine and nitrogen-containing heterocycle.
• Chemical Biology Probe Synthesis: Employed in constructing molecular probes for studying enzyme function and biological pathways in academic and industrial research.
• Material Science Research: Investigated as a monomer or functional additive for advanced polymers and specialty materials requiring specific electronic or binding properties.

Basic Information

Product Name	3-Fluoro-4-[(1-Methyl-1H-Pyrazol-5-Yl)Methoxy]Aniline
CAS No.	1245823-52-2
Molecular Formula	C11H12FN3O
Molecular Weight	221.23 g/mol
Synonyms	3-Fluoro-4-[(1-methyl-1H-pyrazol-5-yl)methoxy]benzenamine; 4-[(1-Methyl-1H-pyrazol-5-yl)methoxy]-3-fluoroaniline; 3-Fluoro-4-((1-methyl-1H-pyrazol-5-yl)methoxy)aniline; 1-Methyl-5-((2-fluoro-4-aminophenoxy)methyl)-1H-pyrazole; 1245823-52-2; 3-Fluoro-4-[(1-methylpyrazol-5-yl)methoxy]aniline
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-[(1-Methyl-1H-Pyrazol-5-Yl)Methoxy]Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.