Description

2-Chlorothieno[3,2-D]Pyrimidin-4(3H)-One is a high-value heterocyclic building block and key synthetic intermediate in modern organic chemistry. This compound matters for its crucial role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers need this precise chemical scaffold to drive innovation in drug discovery and material science programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used as a core structure for developing new fungicides and herbicides with novel modes of action.
• Material Science: Serves as a building block for organic electronic materials and advanced polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biological studies.
• Academic & Contract Research: Essential for methodology development and exploratory synthesis in university and CRO laboratories.
• Custom Synthesis: A starting point for the contract manufacturing of complex, proprietary molecules for clients.

Basic Information

Product Name	2-Chlorothieno[3,2-D]Pyrimidin-4(3H)-One
CAS No.	1245811-20-4
Molecular Formula	C6H3ClN2OS
Molecular Weight	186.62 g/mol
Synonyms	2-Chlorothieno[3,2-d]pyrimidin-4(3H)-one; 4(3H)-Thieno[3,2-d]pyrimidinone, 2-chloro-; 2-Chloro-3,4-dihydrothieno[3,2-d]pyrimidin-4-one; 2-Chloro-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine; 1245811-20-4; Thienopyrimidinone derivative
EINECS	Contact for details

Quality Control

Our 2-Chlorothieno[3,2-D]Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.