Description

Ethyl 7-Cyclopropyl-2-Phenylpyrazolo-[1,5-A]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Employed in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), particularly those with pyrazolopyrimidine cores.
• Biochemical Tool Compound: Serves as a reference standard or inhibitor in biochemical assays to study specific enzymatic pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Used in university and institutional labs for fundamental research in heterocyclic chemistry and drug design.

Basic Information

Product Name	Ethyl 7-Cyclopropyl-2-Phenylpyrazolo-[1,5-A]Pyrimidine-6-Carboxylate
CAS No.	1245808-03-0
Molecular Formula	C₁₈H₁₇N₃O₂
Molecular Weight	307.35 g/mol
Synonyms	7-Cyclopropyl-2-phenylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester; Ethyl 7-cyclopropyl-2-phenylpyrazolo[1,5-a]pyrimidine-6-carboxylate; 1245808-03-0; Pyrazolo[1,5-a]pyrimidine-6-carboxylate, ethyl 7-cyclopropyl-2-phenyl-; SCHEMBL23306277; ZINC000253903791; AKOS040757623; BDBM50389352
EINECS	Contact for details

Quality Control

Our Ethyl 7-Cyclopropyl-2-Phenylpyrazolo-[1,5-A]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.