Description

4-Chloro-6-Methoxypyrimidine-2-Carbaldehyde is a high-purity, versatile pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for research and development in the pharmaceutical and agrochemical sectors, where it is valued for its reactive aldehyde and halogenated pyrimidine functionalities. It is primarily sought after by R&D chemists and process development scientists for constructing complex heterocyclic molecules, including potential active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Chemical Research: Serves as a versatile scaffold for constructing complex heterocyclic libraries in medicinal and combinatorial chemistry.
• Material Science: Potential building block for the development of specialty polymers and organic electronic materials.
• Cross-Coupling Reactions: The chloro-substituent makes it a suitable substrate for palladium-catalyzed reactions like Suzuki-Miyaura couplings.
• Nucleophilic Substitution: The aldehyde group allows for further functionalization via condensation, reduction, or nucleophilic addition reactions.

Basic Information

Product Name	4-Chloro-6-Methoxypyrimidine-2-Carbaldehyde
CAS No.	1245648-65-0
Molecular Formula	C6H5ClN2O2
Molecular Weight	172.57 g/mol
Synonyms	4-Chloro-6-methoxy-2-pyrimidinecarboxaldehyde; 2-Formyl-4-chloro-6-methoxypyrimidine; 4-Chloro-6-methoxypyrimidine-2-carboxaldehyde; 6-Methoxy-4-chloropyrimidine-2-carbaldehyde; 2-Pyrimidinecarboxaldehyde, 4-chloro-6-methoxy-; 4-Chloro-6-methoxy-2-formylpyrimidine
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-6-Methoxypyrimidine-2-Carbaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.