Description

4(3H)-Pyrimidinone, 6-Amino-5-(2,2-Diethoxyethyl)-2-[[4-[2-(1-Pyrrolidinyl)Ethoxy]Phenyl]Amino]- is a sophisticated pyrimidinone derivative, a key advanced intermediate in modern pharmaceutical research and development. Its complex molecular architecture, featuring amino, diethoxyethyl, and pyrrolidinyl ethoxyphenylamino substituents, makes it a critical building block for synthesizing novel therapeutic agents. This high-purity compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Kinase Inhibitor Research: Used in the development and optimization of potential kinase inhibitors due to its pyrimidinone core structure.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies and lead compound optimization in drug discovery programs.
• Biochemical Research: Employed as a tool compound or reference standard in biochemical assays to study enzyme interactions and cellular processes.
• Fine Chemical Synthesis: Acts as a specialized building block for the custom synthesis of complex, high-value organic molecules for research purposes.
• Contract Research & Development (CRO): Supplied to CROs and academic institutions engaged in cutting-edge pharmaceutical and life sciences research.

Basic Information

Product Name	4(3H)-Pyrimidinone, 6-Amino-5-(2,2-Diethoxyethyl)-2-[[4-[2-(1-Pyrrolidinyl)Ethoxy]Phenyl]Amino]-
CAS No.	1245648-59-2
Molecular Formula	C21H31N5O4
Molecular Weight	417.51 g/mol
Synonyms	6-Amino-5-(2,2-diethoxyethyl)-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4(3H)-one; 6-Amino-5-(2,2-diethoxyethyl)-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4(3H)-pyrimidinone; 1245648-59-2; UNII-9G1Q9Q2Q3F; 9G1Q9Q2Q3F; CHEMBL3186302; AKOS025147064; CS-0446646
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to strict quality management systems. Every batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with the standards expected in GMP-oriented research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.