Description

7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine, 7-[(4-Methylphenyl)Sulfonyl]-4-(4-Methyl-2-Thienyl)-n-[4-(4-Morpholinylmethyl)Phenyl]- is a high-purity, advanced pharmaceutical intermediate designed for research and development in targeted drug discovery. This compound is critical for medicinal chemists exploring novel kinase inhibitors and other small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring a reliable supply of complex heterocyclic building blocks for preclinical and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry: Serves as a critical starting material or intermediate in the scale-up and route development of active pharmaceutical ingredients (APIs).
• Biochemical Research: Potential tool compound for studying specific enzymatic pathways and cellular signaling mechanisms.
• Custom Synthesis: Basis for the preparation of more complex, proprietary molecules for client-specific drug discovery projects.
• Reference Standard: High-purity material for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine, 7-[(4-Methylphenyl)Sulfonyl]-4-(4-Methyl-2-Thienyl)-n-[4-(4-Morpholinylmethyl)Phenyl]-
CAS No.	1245648-55-8
Molecular Formula	C29H31N5O3S2
Molecular Weight	561.72 g/mol
Synonyms	7-[(4-Methylphenyl)sulfonyl]-4-(4-methyl-2-thienyl)-N-[4-(4-morpholinylmethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine; 7-(p-Tolylsulfonyl)-4-(4-methyl-2-thienyl)-N-[4-(morpholin-4-ylmethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine; 1245648-55-8; UNII-7Q8K5V8W8K; 7H-Pyrrolo[2,3-d]pyrimidin-2-amine, 7-[(4-methylphenyl)sulfonyl]-4-(4-methyl-2-thienyl)-N-[4-(4-morpholinylmethyl)phenyl]-; 7-(4-Methylbenzenesulfonyl)-4-(4-methylthiophen-2-yl)-N-[4-(morpholin-4-ylmethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. We implement strict in-process controls and final release testing, including identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Our quality management system supports development under cGMP guidelines as required for preclinical and clinical-stage materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.