Description

L-β-Homoserine-Hcl CAS NO 1245645-62-8 is a high-purity, non-proteinogenic amino acid derivative, specifically the hydrochloride salt of L-β-homoserine. This compound serves as a critical chiral building block and biochemical precursor in advanced organic synthesis and pharmaceutical research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing novel therapeutics, peptide mimetics, and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel antibiotics, enzyme inhibitors, and other biologically active compounds.
• Peptide Chemistry: Used in the preparation of modified peptides and peptidomimetics to study structure-activity relationships and enhance metabolic stability.
• Biochemical Research: Acts as a precursor or analog in metabolic pathway studies, particularly those related to homoserine and methionine biosynthesis.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to introduce chiral centers.
• Agrochemical Development: A potential building block for creating new, targeted plant growth regulators or herbicides.
• Cosmetic Actives: Investigated for use in the synthesis of specialty amino acid derivatives for advanced skincare formulations.

Basic Information

Product Name	L-β-Homoserine-Hcl
CAS No.	1245645-62-8
Molecular Formula	C5H12ClNO3
Molecular Weight	169.61 g/mol
Synonyms	L-β-Homoserine hydrochloride; (2S)-2-Amino-4-hydroxybutanoic acid hydrochloride; H-Hse(Bzl)-OH·HCl; L-2-Amino-4-hydroxybutyric acid hydrochloride; β-Homoserine, L-, hydrochloride; L-Threonine isomer hydrochloride; 4-Hydroxy-L-norvaline hydrochloride
EINECS	Contact for details

Quality Control

Our L-β-Homoserine-Hcl is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) documenting identity, purity (typically ≥98% by HPLC), and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]²⁰D: Specific range provided on COA
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.