Description

5-Bromo-2-(2,2,2-trifluoroethyl)aminopyrimidine is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique trifluoroethylamino and bromo substituents, which are essential for modulating the physicochemical and biological properties of target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Used as a precursor in the creation of advanced herbicides, fungicides, and pesticides with enhanced efficacy.
• Chemical Biology Probe Development: Employed in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and fluorine chemistry.

Basic Information

Product Name	5-Bromo-2-(2,2,2-Trifluoroethyl)Aminopyrimidine
CAS No.	1245563-08-9
Molecular Formula	C6H6BrF3N3
Molecular Weight	255.03 g/mol
Synonyms	5-Bromo-2-[(2,2,2-trifluoroethyl)amino]pyrimidine; 2-Amino-5-bromo-N-(2,2,2-trifluoroethyl)pyrimidine; 5-Bromo-2-(2,2,2-trifluoroethylamino)pyrimidine; 1245563-08-9; 5-Bromo-2-((2,2,2-trifluoroethyl)amino)pyrimidine; 2-Pyrimidinamine, 5-bromo-N-(2,2,2-trifluoroethyl)-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(2,2,2-trifluoroethyl)aminopyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.