Description

2-(4-(6-((5-((2-Chloro-6-Methylphenyl)Carbamoyl)Thiazol-2-Yl)Amino)-2-Methylpyrimidin-4-Yl)Piperazin-1-Yl)Ethyl Acetate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in oncology and targeted disease pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of investigational new drugs (INDs) and novel chemical entities (NCEs).
• Oncology Research: Used in the development of targeted cancer therapies, including kinase inhibitors and other small molecule drugs.
• Medicinal Chemistry: A crucial reagent for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Employed as a tool compound for studying specific enzyme interactions and biological pathways.
• Custom Synthesis: Supplied to fine chemical companies for the contract manufacturing of complex, high-value APIs.
• Preclinical Development: Used in the production of materials for toxicology studies and formulation development.

Basic Information

Product Name	2-(4-(6-((5-((2-Chloro-6-Methylphenyl)Carbamoyl)Thiazol-2-Yl)Amino)-2-Methylpyrimidin-4-Yl)Piperazin-1-Yl)Ethyl Acetate
CAS No.	1245157-85-0
Molecular Formula	C24H27ClN8O3S
Molecular Weight	543.04 g/mol
Synonyms	1245157-85-0; Ethyl 2-[4-[6-[[5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazol-2-yl]amino]-2-methylpyrimidin-4-yl]piperazin-1-yl]acetate; 2-(4-(6-((5-((2-Chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)amino)-2-methylpyrimidin-4-yl)piperazin-1-yl)ethyl acetate; UNII-4H8J8S3Q0K; 4H8J8S3Q0K; CHEMBL3186660; AKOS025147223; CS-0446599.
EINECS	Contact for details

Quality Control

Our 2-(4-(6-((5-((2-Chloro-6-Methylphenyl)Carbamoyl)Thiazol-2-Yl)Amino)-2-Methylpyrimidin-4-Yl)Piperazin-1-Yl)Ethyl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.