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tert-Butyl 2,6-Dichloropyrimidin-4-Ylcarbamate CAS NO 1244949-72-1


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CAS No.:1244949-72-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

tert-Butyl 2,6-Dichloropyrimidin-4-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate and versatile chemical building block. This compound is of significant commercial importance for its role as a key synthon in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing complex molecules.

Application

  • Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, particularly in medicinal chemistry research and API development.
  • Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the pyrimidine core is a key structural motif.
  • Organic Synthesis Reagent: Serves as a versatile electrophile in cross-coupling reactions, nucleophilic substitutions, and other transformations to construct heterocyclic systems.
  • Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.
  • Material Science Precursor: Potential use in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional polymers.

Basic Information

Item Detail
Product Name tert-Butyl 2,6-Dichloropyrimidin-4-Ylcarbamate
CAS No. 1244949-72-1
Molecular Formula C9H11Cl2N3O2
Molecular Weight 264.11 g/mol
Synonyms tert-Butyl (2,6-dichloropyrimidin-4-yl)carbamate; 2,6-Dichloro-N-(tert-butoxycarbonyl)pyrimidin-4-amine; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2,6-dichloropyrimidine; 2,6-Dichloropyrimidin-4-yl-carbamic acid tert-butyl ester; BOC-2,6-Dichloropyrimidin-4-amine; tert-Butyl N-(2,6-dichloropyrimidin-4-yl)carbamate
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Quality Control

Our tert-Butyl 2,6-Dichloropyrimidin-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) documenting full specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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