Description

3-Ethyl-4-Fluorophenol is a fluorinated phenolic compound of significant interest in advanced organic synthesis. Its value lies in its role as a versatile building block, where the ethyl and fluorine substituents on the phenol core allow for precise tuning of electronic and steric properties in target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for display technologies.
• Polymer Science: Acts as a monomer or modifier in the production of specialty polymers, such as polyarylates and epoxy resins, to impart specific thermal or chemical resistance.
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials due to its electron-withdrawing characteristics.
• Chemical Research: A valuable reagent for method development in cross-coupling reactions and other catalytic transformations in academic and industrial laboratories.

Basic Information

Product Name	3-Ethyl-4-Fluorophenol
CAS No.	1243455-57-3
Molecular Formula	C8H9FO
Molecular Weight	140.16 g/mol
Synonyms	4-Fluoro-3-ethylphenol; 3-Ethyl-4-fluorophenol; 1-Ethyl-2-fluoro-4-hydroxybenzene; 2-Fluoro-5-ethylphenol; 5-Ethyl-2-fluorophenol; Phenol, 3-ethyl-4-fluoro-; 4-Hydroxy-2-fluoroethylbenzene
EINECS	Contact for details

Quality Control

Our 3-Ethyl-4-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.