Description

3-tert-Butyl-2-Fluorophenol is a specialized fluorinated phenolic compound that serves as a versatile intermediate in advanced organic synthesis. Its unique structure, combining a sterically hindered tert-butyl group with a fluorine atom on the phenol ring, makes it valuable for modulating the electronic and steric properties of target molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for introducing fluorine to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorophenol moiety contributes to biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing monomers and additives that improve the performance of electronic display materials.
• Polymer Modification: Acts as a functional monomer or stabilizer in the production of high-performance, specialty polymers.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A valuable reagent for academic and industrial research exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	3-tert-Butyl-2-Fluorophenol
CAS No.	1243450-69-2
Molecular Formula	C10H13FO
Molecular Weight	168.21 g/mol
Synonyms	2-Fluoro-3-tert-butylphenol; 3-(tert-Butyl)-2-fluorophenol; 2-Fluoro-3-(1,1-dimethylethyl)phenol; Phenol, 3-(1,1-dimethylethyl)-2-fluoro-; 3-tert-Butyl-2-fluorophenol; 3-tert-Butyl-2-fluoro-1-hydroxybenzene; 2-Fluoro-3-tert-butyl-1-hydroxybenzene
EINECS	Contact for details

Quality Control

Our 3-tert-Butyl-2-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.