Description

Fmoc-Lys(5-Fam)-Oh CAS NO 1242933-88-5 is a specialized, fluorescently-labeled amino acid derivative used in advanced peptide synthesis and biochemical research. This compound is critical for researchers and manufacturers who require site-specific fluorescent tagging to study protein-protein interactions, cellular localization, and peptide structure-function relationships. It is an essential building block for the pharmaceutical, biotechnology, and diagnostic industries, enabling the development of novel probes, therapeutics, and high-throughput screening assays.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a fluorescently-modified lysine derivative for the controlled incorporation of fluorophores into synthetic peptides.
• Bioconjugation & Probe Development: For creating fluorescently-labeled peptides used as molecular probes in imaging and diagnostic applications.
• Biochemical Research: Enabling fluorescence resonance energy transfer (FRET) studies to investigate peptide conformation, dynamics, and binding events.
• Pharmaceutical R&D: Facilitating the development of peptide-based drug candidates with traceable pharmacokinetic and biodistribution profiles.
• Diagnostic Assay Reagents: Serving as a key component in the synthesis of reagents for ELISA, flow cytometry, and other fluorescence-based detection systems.
• Material Science: Used in the fabrication of biofunctionalized surfaces and smart biomaterials where fluorescent signaling is required.

Basic Information

Product Name	Fmoc-Lys(5-Fam)-Oh
CAS No.	1242933-88-5
Molecular Formula	C41H41N3O9
Molecular Weight	719.79 g/mol
Synonyms	Fmoc-Lys(5-FAM)-OH; N-α-Fmoc-N-ε-(5-carboxyfluorescein)-L-lysine; Fmoc-Lys(FAM)-OH; 5(6)-FAM labeled Fmoc-Lysine; Fluorescein labeled Fmoc-Lysine; Nε-(5-Carboxyfluorescein)-Nα-(9-fluorenylmethoxycarbonyl)-L-lysine; Fmoc-L-lysine(5-FAM); Fmoc-Lys(5(6)-FAM)-OH
EINECS	Contact for details

Quality Control

Every batch of Fmoc-Lys(5-Fam)-Oh is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and performance consistency. We provide full traceability and Certificates of Analysis (COA) detailing HPLC purity, chiral purity, and other critical parameters. Our quality commitment aligns with the standards required for research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is strictly light-sensitive (protect from all light exposure) and hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, keep under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Solubility	Soluble in DMF, DMSO; slightly soluble in acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.