Description

4-Chloro-2-Fluoro-[1,1-Biphenyl]-3-Carbaldehyde is a high-purity fluorinated biphenyl derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique halogenated aromatic structure, which provides versatile reactivity for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated biphenyl core.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of fluorinated components for electronic display technologies and organic light-emitting diodes.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and specialty chemicals with tailored properties.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4-Chloro-2-Fluoro-[1,1-Biphenyl]-3-Carbaldehyde
CAS No.	1242339-63-4
Molecular Formula	C₁₃H₈ClFO
Molecular Weight	234.65 g/mol
Synonyms	4-Chloro-2-fluorobiphenyl-3-carboxaldehyde; 3-Formyl-4-chloro-2-fluorobiphenyl; [1,1'-Biphenyl]-3-carboxaldehyde, 4-chloro-2-fluoro-; 4-Chloro-2-fluoro-3-biphenylcarbaldehyde; 2-Fluoro-4-chlorobiphenyl-3-carbaldehyde; 4-Chloro-2-fluoro-[1,1'-biphenyl]-3-carbaldehyde; 3-Biphenylcarboxaldehyde, 4-chloro-2-fluoro-
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoro-[1,1-Biphenyl]-3-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.