Description

5-Chloro-4-Fluoro-2-Methylaniline is a high-purity, halogenated aniline derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic core for constructing complex molecules with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aniline motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the chloro and fluoro substituents enhance biological activity.
• Dye and Pigment Manufacturing: Serves as a starting material for producing specialized azo dyes and organic pigments with specific color fastness and stability properties.
• Material Science Research: Employed in the creation of advanced polymers, liquid crystals, and electronic materials that incorporate functional aniline units.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing heterocycles.

Basic Information

Product Name	5-Chloro-4-Fluoro-2-Methylaniline
CAS No.	1242339-43-0
Molecular Formula	C7H7ClFN
Molecular Weight	159.59 g/mol
Synonyms	2-Methyl-5-chloro-4-fluoroaniline; 4-Fluoro-5-chloro-2-methylaniline; 5-Chloro-4-fluoro-o-toluidine; 2-Amino-5-chloro-4-fluorotoluene; Benzenamine, 5-chloro-4-fluoro-2-methyl-; 5-Chloro-4-fluoro-2-methylbenzenamine
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Fluoro-2-Methylaniline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.