Description

(4-(Difluoromethoxy)-3-Fluorophenyl)Methanol is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in its unique difluoromethoxy and fluorophenyl structure, which is crucial for modulating the physicochemical properties of target molecules. This compound is primarily needed by R&D and process development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorine atoms to improve metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorinated moiety can enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays, leveraging its aromatic and fluorine content.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and electro-optical materials due to its electron-withdrawing characteristics.
• Chemical Research & Development: A versatile building block for academic and industrial research in medicinal chemistry, materials science, and fluorine chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	(4-(Difluoromethoxy)-3-Fluorophenyl)Methanol
CAS No.	1242252-59-0
Molecular Formula	C8H7F3O2
Molecular Weight	192.14 g/mol
Synonyms	(4-(Difluoromethoxy)-3-fluorophenyl)methanol; [4-(Difluoromethoxy)-3-fluorophenyl]methanol; 3-Fluoro-4-(difluoromethoxy)benzyl alcohol; 1-[4-(Difluoromethoxy)-3-fluorophenyl]methanol; Benzyl alcohol, 3-fluoro-4-(difluoromethoxy)-; (3-Fluoro-4-(difluoromethoxy)phenyl)methanol
EINECS	Contact for details

Quality Control

Every batch of (4-(Difluoromethoxy)-3-Fluorophenyl)Methanol undergoes rigorous analytical testing to ensure it meets the high standards required for sensitive synthetic applications. Our quality assurance protocol includes identity confirmation, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.