Description

4-(4-(Methylsulfonyl)Phenoxy)-2-Chloropyrimidine is a high-purity, advanced pharmaceutical intermediate with a distinct molecular structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within oncology and anti-inflammatory research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug molecules and investigational new chemical entities.
• Kinase Inhibitor Research: Used in the development and optimization of kinase inhibitor candidates due to its pyrimidine core.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for biochemical and pharmacological studies.
• Agrochemical Intermediate: Potential application in the synthesis of novel crop protection agents.

Basic Information

Product Name	4-(4-(Methylsulfonyl)Phenoxy)-2-Chloropyrimidine
CAS No.	1242240-94-3
Molecular Formula	C11H9ClN2O3S
Molecular Weight	284.72 g/mol
Synonyms	2-Chloro-4-[(4-methylsulfonyl)phenoxy]pyrimidine; 4-(4-Methanesulfonylphenoxy)-2-chloropyrimidine; 2-Chloro-4-(4-(methylsulfonyl)phenoxy)pyrimidine; 4-(p-Methylsulfonylphenoxy)-2-chloropyrimidine; 2-Chloropyrimidine, 4-[(4-(methylsulfonyl)phenyl)oxy]-; CAS 1242240-94-3
EINECS	Contact for details

Quality Control

Our 4-(4-(Methylsulfonyl)Phenoxy)-2-Chloropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development and commercial projects with material produced to GMP-grade standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.