Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-(4-Ethyl-1-Piperazinyl)-6-Fluoro-1,4-Dihydro-4-Oxo-, 2-(1,1-Dimethylethoxy)-2-Oxoethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial interest due to its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel fluoroquinolone antibiotics.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for creating new antibacterial compounds.
• Chemical Synthesis Research: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and structure-activity relationships.
• Process Chemistry & Scale-Up: Utilized in optimizing synthetic routes and scaling production from laboratory to pilot plant and commercial manufacturing.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API production.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-(4-Ethyl-1-Piperazinyl)-6-Fluoro-1,4-Dihydro-4-Oxo-, 2-(1,1-Dimethylethoxy)-2-Oxoethyl Ester
CAS No.	1242012-53-8
Molecular Formula	C24H30FN3O5
Molecular Weight	459.52 g/mol
Synonyms	1-Cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 2-tert-butoxy-2-oxoethyl ester; 2-(tert-Butoxy)-2-oxoethyl 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate; 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(4-ethyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid (1,1-dimethylethoxy)carbonylmethyl ester; Fluoroquinolone Ester Intermediate; Quinolone Carboxylic Acid Ester Derivative; Garenoxacin Intermediate (related derivative); Advanced Fluoroquinolone Building Block
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid Ester intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment. We can support development projects with custom purity grades and specifications aligned with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under controlled conditions to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.