Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-(4-Ethyl-1-Piperazinyl)-6-Fluoro-1,4-Dihydro-4-Oxo-, 2-(4-Fluorophenoxy)Ethyl Ester is a high-purity, complex organic compound designed for advanced pharmaceutical research and development. This molecule is a key synthetic intermediate, valued for its specific structural motifs that are critical in the design of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of next-generation therapeutics, particularly in the areas of antibacterial and anti-infective agents.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel quinolone and fluoroquinolone antibiotic candidates.
• Antibacterial Research: Used in medicinal chemistry programs targeting DNA gyrase and topoisomerase IV inhibition for new anti-infective drugs.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Process Chemistry Development: Employed in route scouting and optimization studies for scalable API production.
• Academic & Institutional Research: Utilized in university and research institute labs for studying structure-activity relationships (SAR) in heterocyclic chemistry.
• Custom Synthesis: A starting material for the preparation of more complex, tailored molecular entities for client-specific drug discovery projects.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-(4-Ethyl-1-Piperazinyl)-6-Fluoro-1,4-Dihydro-4-Oxo-, 2-(4-Fluorophenoxy)Ethyl Ester
CAS No.	1242005-98-6
Molecular Formula	C27H29F2N3O4
Molecular Weight	497.54 g/mol
Synonyms	2-(4-Fluorophenoxy)ethyl 1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid 2-(4-Fluorophenoxy)ethyl Ester; Garenoxacin Ethoxy Ester; Garenoxacin Intermediate; T-3811ME; AM-1155 Ester; 6-Fluoro-1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid 2-(4-Fluorophenoxy)ethyl Ester
EINECS	Contact for details

Quality Control

Every batch of this pharmaceutical intermediate is produced and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring traceability and compliance with cGMP guidelines for advanced intermediates. Our analytical methods, including HPLC, NMR, and MS, are validated to confirm the chemical identity and meet the stringent specifications required for pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.