Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-(4-Ethyl-1-Piperazinyl)-6-Fluoro-1,4-Dihydro-4-Oxo-, 2-Methoxy-2-Oxoethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of next-generation antibacterial agents, offering a key building block for targeted drug development. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel fluoroquinolone antibiotics and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone-class antibacterial drugs.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for new antibiotic compounds.
• Biochemical Research: Serves as a standard or reagent in studies targeting bacterial DNA gyrase and topoisomerase IV enzymes.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for complex heterocyclic molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-(4-Ethyl-1-Piperazinyl)-6-Fluoro-1,4-Dihydro-4-Oxo-, 2-Methoxy-2-Oxoethyl Ester
CAS No.	1241997-93-2
Molecular Formula	C22H26FN3O5
Molecular Weight	431.46 g/mol
Synonyms	1-Cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 2-methoxy-2-oxoethyl ester; Gatifloxacin Ethyl Ester; Gatifloxacin Precursor; Ethyl 1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (common misnomer); 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(4-ethyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid (carboxymethyl) methyl ester; Gatifloxacine Ester Intermediate; AM-1155 Ester
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid Ester intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.