Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-(4-Ethyl-1-Piperazinyl)-6-Fluoro-1,4-Dihydro-4-Oxo-, (3-Chlorophenyl)Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation antibacterial or targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly fluoroquinolone analogs and other antibacterial agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes for discovering new drug candidates.
• Process Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Custom Synthesis: A starting material for the custom synthesis of specialized compounds for biological screening and testing.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-(4-Ethyl-1-Piperazinyl)-6-Fluoro-1,4-Dihydro-4-Oxo-, (3-Chlorophenyl)Methyl Ester
CAS No.	1241970-22-8
Molecular Formula	C26H27ClFN3O3
Molecular Weight	483.97 g/mol
Synonyms	(3-Chlorophenyl)methyl 1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid (3-Chlorophenyl)Methyl Ester; GSK-2140944B; GSK2140944B; GSK 2140944B; 1241970-22-8; 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-, (3-chlorophenyl)methyl ester
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-(4-Ethyl-1-Piperazinyl)-6-Fluoro-1,4-Dihydro-4-Oxo-, (3-Chlorophenyl)Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.