Description

2,6-Dihydroxy-D-Phenylalanine is a specialized, non-proteinogenic amino acid derivative of DOPA, distinguished by its unique 2,6-dihydroxy substitution pattern on the phenyl ring. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential role as a chiral building block or a precursor in the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic agents, and biochemical tools. Its high purity and defined stereochemistry are critical for ensuring reproducibility and efficacy in sensitive applications.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel drug candidates, particularly for neurological and metabolic disorders.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate catecholamine biosynthesis and related metabolic pathways.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for method development and quality control.
• Precursor for Specialty Chemicals: Acts as a starting material for the synthesis of more complex molecules, including labeled compounds for tracer studies.
• Neuroscience Research: Investigated for its potential effects on dopaminergic systems and as a tool compound in neuropharmacology.

Basic Information

Product Name	2,6-Dihydroxy-D-Phenylalanine
CAS No.	1241678-01-2
Molecular Formula	C9H11NO5
Molecular Weight	213.19 g/mol
Synonyms	2,6-Dihydroxy-DOPA; (2R)-2-Amino-3-(2,6-dihydroxyphenyl)propanoic acid; D-2,6-Dihydroxyphenylalanine; 2,6-DiOH-D-Phe; 1241678-01-2; (R)-2-Amino-3-(2,6-dihydroxyphenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our 2,6-Dihydroxy-D-Phenylalanine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical purity, and impurity profiles. We adhere to relevant industry guidelines for research-grade chemicals, and specifications can be tailored to meet specific project requirements. COAs are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.