Description

(1R)-1-[3-Fluoro-4-(Trifluoromethyl)Phenyl]Propylamine is a chiral amine building block of significant interest in advanced organic synthesis. Its core value lies in its unique trifluoromethyl and fluorine-substituted aromatic structure, which is highly sought after for modulating the physicochemical properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disease therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored electronic or surface properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or molecular probes in biochemical research.

Basic Information

Product Name	(1R)-1-[3-Fluoro-4-(Trifluoromethyl)Phenyl]Propylamine
CAS No.	1241677-13-3
Molecular Formula	C10H11F4N
Molecular Weight	221.20 g/mol
Synonyms	(R)-1-(3-Fluoro-4-(trifluoromethyl)phenyl)propan-1-amine; (1R)-1-[3-Fluoro-4-(trifluoromethyl)phenyl]propan-1-amine; (R)-3-Fluoro-α-(trifluoromethyl)benzenepropanamine; (R)-1-(3-Fluoro-4-(trifluoromethyl)phenyl)propylamine; (R)-α-Methyl-3-fluoro-4-(trifluoromethyl)benzeneethanamine; (R)-3-Fluoro-4-(trifluoromethyl)amphetamine (structural analog); (R)-FTPA (abbreviation)
EINECS	Contact for details

Quality Control

Our (1R)-1-[3-Fluoro-4-(Trifluoromethyl)Phenyl]Propylamine is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.