Description

(4-(Trifluoromethyl)Pyrimidin-2-Yl)Methanol is a high-value pyrimidine derivative, a crucial building block in advanced organic synthesis. Its core value lies in the trifluoromethyl group, which significantly enhances the metabolic stability, lipophilicity, and bioavailability of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, particularly in kinase inhibitors, antiviral agents, and anti-cancer therapies.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, leveraging the CF3 group for improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty chemicals, ligands, and functional materials requiring fluorinated heterocyclic structures.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes and activity-based protein profiling (ABPP) agents.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(4-(Trifluoromethyl)Pyrimidin-2-Yl)Methanol
CAS No.	1240594-67-5
Molecular Formula	C6H5F3N2O
Molecular Weight	178.11 g/mol
Synonyms	2-(Hydroxymethyl)-4-(trifluoromethyl)pyrimidine; (4-Trifluoromethyl-2-pyrimidinyl)methanol; 4-(Trifluoromethyl)-2-pyrimidinemethanol; 2-Pyrimidinemethanol, 4-(trifluoromethyl)-; (4-(Trifluoromethyl)pyrimidin-2-yl)methanol
EINECS	Contact for details

Quality Control

Our (4-(Trifluoromethyl)Pyrimidin-2-Yl)Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, it is recommended to keep the material under an inert atmosphere at temperatures between 2°C and 8°C to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.