Description

2-Fluoro-5-(Pentafluorosulfur)Aniline is a high-value, fluorinated aromatic amine building block characterized by its unique combination of fluorine and pentafluorosulfur substituents. This compound is critical for introducing specific electronic and steric properties into advanced molecular architectures, enabling the development of novel materials and active ingredients. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for applications in drug discovery, crop protection, and functional polymer synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine and SF5 groups enhance biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, contributing to the dielectric anisotropy and thermal stability of liquid crystal mixtures and organic light-emitting diode (OLED) components.
• Polymer & Resin Modification: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, and tailored reactivity for high-performance coatings and adhesives.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a precursor for more complex heterocyclic and fluorinated compounds in organic synthesis.

Basic Information

Product Name	2-Fluoro-5-(Pentafluorosulfur)Aniline
CAS No.	1240257-94-6
Molecular Formula	C6H3F6NS
Molecular Weight	235.15 g/mol
Synonyms	2-Fluoro-5-(pentafluoro-λ6-sulfanyl)aniline; 2-Fluoro-5-(SF5)aniline; 5-Amino-2-fluorophenylsulfur pentafluoride; Benzenamine, 2-fluoro-5-(pentafluorosulfur)-; 2-Fluoro-5-pentafluorosulfanylaniline; 2-Fluoro-5-(sulfur pentafluoride)aniline; 2-Fluoro-5-(SF5)C6H3NH2
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(Pentafluorosulfur)Aniline is manufactured and analyzed under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via HPLC, GC, NMR, and IR is supplied with each shipment. Our quality system is designed to support cGMP and ISO standards for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.