Description

2-Fluoro-4-(Pentafluorosulfur)Benzylamine is a high-value, fluorinated benzylamine derivative characterized by its unique pentafluorosulfur (SF5) functional group. This compound serves as a critical advanced building block in modern synthetic chemistry, enabling the introduction of both fluorine and the highly lipophilic, metabolically stable SF5 moiety into target molecules. It is primarily sought after by pharmaceutical researchers and agrochemical developers for the creation of novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in areas requiring improved metabolic stability and membrane permeability.
• Agrochemical Research: Building block for novel herbicides, fungicides, and insecticides where the SF5 group can enhance bioactivity and environmental persistence.
• Material Science: Precursor for specialty polymers, liquid crystals, and electronic materials benefiting from the unique electronic properties of the SF5 group.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to explore the "fluorine effect" and the influence of super-trifluoromethyl groups.
• Chemical Biology: Incorporation into probes and ligands for studying biological systems and protein interactions.
• Advanced Organic Synthesis: Serves as a versatile amine component in amide coupling, reductive amination, and other C-N bond-forming reactions.

Basic Information

Product Name	2-Fluoro-4-(Pentafluorosulfur)Benzylamine
CAS No.	1240257-86-6
Molecular Formula	C7H5F6NS
Molecular Weight	249.18 g/mol
Synonyms	(2-Fluoro-4-((pentafluoro-λ6-sulfanyl)phenyl))methanamine; 4-(Aminomethyl)-3-fluoro-1-(pentafluoro-λ6-sulfanyl)benzene; 2-Fluoro-4-(SF5)benzylamine; 2-Fluoro-4-pentafluorosulfanylbenzylamine; α-Amino-2-fluoro-4-pentafluorosulfanyltoluene; 1-(Aminomethyl)-2-fluoro-4-(pentafluorosulfur)benzene; 2-Fluoro-4-(pentafluorosulfanyl)benzenemethanamine
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(Pentafluorosulfur)Benzylamine is manufactured and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, GC, NMR, and IR spectroscopy. Our production adheres to cGMP principles where applicable, ensuring consistency and traceability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.