Description

2-Fluoro-4-(trifluoromethoxy)benzyl bromide, 97% is a high-purity organofluorine building block essential for advanced chemical synthesis. This compound matters as a versatile reagent for introducing the 2-fluoro-4-(trifluoromethoxy)benzyl moiety, a key structural motif that can impart desirable properties like metabolic stability and lipophilicity to target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: Acts as an electrophilic partner in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create complex biaryl structures.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and advanced functional materials with tailored properties.

Basic Information

Product Name	2-Fluoro-4-(trifluoromethoxy)benzyl bromide, 97%
CAS No.	1240257-47-9
Molecular Formula	C8H5BrF4O
Molecular Weight	273.03 g/mol
Synonyms	1-(Bromomethyl)-2-fluoro-4-(trifluoromethoxy)benzene; α-Bromo-2-fluoro-4-(trifluoromethoxy)toluene; 2-Fluoro-α-bromo-4-(trifluoromethoxy)toluene; (2-Fluoro-4-(trifluoromethoxy)phenyl)methyl bromide; 2-Fluoro-4-(trifluoromethoxy)benzyl bromide; 4-(Trifluoromethoxy)-2-fluorobenzyl bromide
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(trifluoromethoxy)benzyl bromide, 97% undergoes rigorous quality testing to ensure compliance with industry standards. Every batch is analyzed using advanced techniques like HPLC, GC, and NMR to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.