Description

3-Bromo-5-(Pentafluorosulfur)Benzaldehyde is a high-value, multi-functional aromatic aldehyde building block distinguished by its unique combination of bromine and pentafluorosulfur substituents. This compound matters for its role in facilitating complex molecular synthesis, offering precise sites for cross-coupling reactions and introducing potent fluorinated functional groups. It is primarily needed by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for creating novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Research: Used in the synthesis of advanced pesticide and herbicide molecules, where the pentafluorosulfur group can enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic display materials and organic light-emitting diodes (OLEDs), improving charge transport and device efficiency.
• Ligand & Catalyst Development: Employed in the design of specialized ligands for transition metal catalysis, leveraging the bromine handle for further functionalization.
• Polymer & Resin Modification: Incorporated into high-performance polymers to impart unique solubility, thermal stability, and surface properties.
• Fluorinated Bioisostere: Acts as a sophisticated building block for introducing the SF5 group as a bioisostere in drug design, a strategy to modulate potency, metabolic stability, and lipophilicity.

Basic Information

Product Name	3-Bromo-5-(Pentafluorosulfur)Benzaldehyde
CAS No.	1240257-22-0
Molecular Formula	C7H2BrF5OS
Molecular Weight	293.06 g/mol
Synonyms	3-Bromo-5-(pentafluoro-λ⁶-sulfanyl)benzaldehyde; 5-Bromo-3-formylbenzenesulfonyl pentafluoride; Benzaldehyde, 3-bromo-5-(pentafluorosulfur)-; 3-Bromo-5-(SF5)benzaldehyde; 3-Bromo-5-sulfurpentafluorobenzaldehyde; (3-Bromo-5-sulfanylpentafluoridanyl)benzaldehyde
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(Pentafluorosulfur)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.