Description

3-Chloro-5-(Pentafluorosulphur)Benzylbromide CAS NO 1240257-05-9 is a high-value, multi-functional organofluorine building block characterized by its unique benzyl bromide and pentafluorosulfur (SF5) functional groups. This compound is essential for introducing the highly electronegative and lipophilic SF5 moiety into target molecules, a key strategy in modern agrochemical and pharmaceutical design. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the SF5 group improves weatherfastness and biological activity.
• Advanced Material Science: Serves as a precursor for specialty polymers, liquid crystals, and electronic materials requiring high thermal and chemical stability.
• Fluorine Chemistry & Catalysis: Employed in methodological studies and as a reagent for introducing fluorinated groups in cross-coupling and nucleophilic substitution reactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting custom synthesis and scale-up projects for global clients.

Basic Information

Product Name	3-Chloro-5-(Pentafluorosulphur)Benzylbromide
CAS No.	1240257-05-9
Molecular Formula	C7H3BrClF5S
Molecular Weight	313.51 g/mol
Synonyms	1-(Bromomethyl)-3-chloro-5-(pentafluoro-λ6-sulfanyl)benzene; (3-Chloro-5-(pentafluorosulfanyl)phenyl)methyl bromide; 3-Chloro-5-(SF5)benzyl bromide; α-Bromo-3-chloro-5-(pentafluorosulfanyl)toluene; 3-Chloro-5-pentafluorosulfur benzyl bromide; Benzene, 1-(bromomethyl)-3-chloro-5-(pentafluoro-λ6-sulfanyl)-; SF5-Benzyl Bromide Derivative
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-(Pentafluorosulphur)Benzylbromide is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring traceability and consistency for your critical R&D and scale-up work. Our quality systems are designed to support regulatory filings, and we can supply material compliant with ICH Q7 guidelines for active pharmaceutical ingredient (API) starting materials upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its reactivity as an organic halide and sensitivity to strong acids/organic solvents, keep away from incompatible materials. This highly volatile compound should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.