Description

1H-Indole-5-Carbonitrile, 4-Fluoro- is a high-purity fluorinated indole derivative, a crucial building block in modern organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical sector where the indole scaffold is a privileged structure. It is primarily needed by research chemists and process development scientists in pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators leveraging the indole moiety.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent in biochemical assays and proteomics research due to its reactive nitrile group.
• Academic & Contract Research: Essential for methodological development in organic chemistry, including cross-coupling and cyclization reactions.

Basic Information

Product Name	1H-Indole-5-Carbonitrile, 4-Fluoro-
CAS No.	1240113-42-1
Molecular Formula	C9H5FN2
Molecular Weight	160.15 g/mol
Synonyms	4-Fluoro-1H-indole-5-carbonitrile; 4-Fluoroindole-5-carbonitrile; 5-Cyano-4-fluoroindole; 4-Fluoro-5-cyanoindole; 1H-Indole-5-carbonitrile, 4-fluoro-; 1240113-42-1; 4-Fluoro-1H-indole-5-CN
EINECS	Contact for details

Quality Control

Our 1H-Indole-5-Carbonitrile, 4-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and REACH compliance ensures reliable supply for global research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.