Description

5-Fluoro-2-Iodo-4-Trifluoromethyl-Phenylamine is a high-purity, multi-functional halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring fluorine, iodine, and trifluoromethyl substituents, makes it an indispensable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by material scientists developing specialty polymers and electronic chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic semiconductors for electronic applications.
• Chemical Biology & Proteomics: Employed as a tagging or cross-linking reagent in probe development for studying protein interactions and enzyme mechanisms.
• Organic Light-Emitting Diodes (OLEDs): Acts as a core building block for electron-transport materials and host molecules in OLED device fabrication.
• Contract Research & Development (CRO/CMO): Supplied to custom synthesis and process development organizations for client-directed research projects and scale-up activities.

Basic Information

Product Name	5-Fluoro-2-Iodo-4-Trifluoromethyl-Phenylamine
CAS No.	1239463-37-6
Molecular Formula	C7H4F4IN
Molecular Weight	320.01 g/mol
Synonyms	4-Amino-5-fluoro-2-iodobenzotrifluoride; 5-Fluoro-2-iodo-4-(trifluoromethyl)aniline; 2-Iodo-5-fluoro-4-trifluoromethylaniline; 4-Trifluoromethyl-5-fluoro-2-iodoaniline; 5-Fluoro-2-iodo-α,α,α-trifluoro-p-toluidine; Benzenamine, 5-fluoro-2-iodo-4-(trifluoromethyl)-; 5-Fluoro-2-iodo-4-trifluoromethylphenylamine
EINECS	Contact for details

Quality Control

Our production of 5-Fluoro-2-Iodo-4-Trifluoromethyl-Phenylamine adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and reliability. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system is designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications, and we can accommodate custom purity specifications (e.g., >98%, >99%) and analytical protocols (HPLC, GC, NMR) to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged procedures to minimize degradation. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.