Description

5-Bromothieno[2,3-D]Pyrimidin-4-Ol is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical candidates, particularly in kinase inhibitor research. It is primarily utilized by medicinal chemists and R&D departments in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially protein kinase inhibitors.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Agrochemical Development: Serves as a building block for creating new active ingredients with potential herbicidal or fungicidal properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes under cGMP conditions.
• Academic Research: Employed in university and institutional labs for methodology development and exploring new heterocyclic chemistry.

Basic Information

Product Name	5-Bromothieno[2,3-D]Pyrimidin-4-Ol
CAS No.	1239460-83-3
Molecular Formula	C6H3BrN2OS
Molecular Weight	231.07 g/mol
Synonyms	5-Bromothieno[2,3-d]pyrimidin-4-ol; 4-Hydroxy-5-bromothieno[2,3-d]pyrimidine; 5-Bromo-4-hydroxythieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidin-4-ol, 5-bromo-; 5-Bromo-4H-thieno[2,3-d]pyrimidin-4-one (tautomer); 5-Bromothienopyrimidinone; 5-Bromo-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromothieno[2,3-D]Pyrimidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.