Description

2(3H)-Benzoxazolone, 5-[[2-[(4-Fluoro-3-Methoxy-5-Methylphenyl)Amino]-5-Methyl-4-Pyrimidinyl]Amino]-3-[(Phosphonooxy)Methyl]- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant interest for its role in the research and development of novel therapeutic agents, particularly in targeted drug discovery programs. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing potent, selective bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of investigational new drugs, especially kinase inhibitors and other targeted therapies.
• Biochemical Research: Used as a reference standard or a key precursor in academic and industrial research focused on enzyme inhibition and signal transduction pathways.
• Preclinical Development: Employed in the production of compounds for pharmacological profiling, toxicology studies, and formulation development.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client-specific drug discovery projects.
• Chemical Biology Probes: Utilized in the development of chemical probes to study specific biological targets and disease mechanisms.

Basic Information

Product Name	2(3H)-Benzoxazolone, 5-[[2-[(4-Fluoro-3-Methoxy-5-Methylphenyl)Amino]-5-Methyl-4-Pyrimidinyl]Amino]-3-[(Phosphonooxy)Methyl]-
CAS No.	1237168-58-9
Molecular Formula	C21H22FN5O6P
Molecular Weight	481.40 g/mol
Synonyms	5-[[2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4-pyrimidinyl]amino]-3-[(phosphonooxy)methyl]-2(3H)-benzoxazolone; 3-(Phosphonooxymethyl)-5-({2-[(4-fluoro-3-methoxy-5-methylphenyl)amino]-5-methylpyrimidin-4-yl}amino)-1,3-benzoxazol-2(3H)-one; UNII-7Q1K2Q8F0W; 7Q1K2Q8F0W; Benzoxazolone derivative CAS 1237168-58-9
EINECS	Contact for details

Quality Control

This product is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Quality is verified through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.