Description

4-(Azetidin-3-Yl)-2-Methylpyrimidine Tfa is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• API Development: Serves as a crucial precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) offering bespoke synthesis services for clinical trial materials.
• Library Synthesis: Used in combinatorial chemistry to create diverse compound libraries for high-throughput screening.

Basic Information

Product Name	4-(Azetidin-3-Yl)-2-Methylpyrimidine Tfa
CAS No.	1236861-81-6
Molecular Formula	C11H14F3N3O2
Molecular Weight	277.24 g/mol
Synonyms	4-(Azetidin-3-yl)-2-methylpyrimidine trifluoroacetate; 2-Methyl-4-(azetidin-3-yl)pyrimidine trifluoroacetic acid salt; 4-(Azetidin-3-yl)-2-methylpyrimidine TFA salt; 4-(3-Azetidinyl)-2-methylpyrimidine trifluoroacetate; 2-Methyl-4-(azetidin-3-yl)pyrimidine TFA; 4-(Azetidin-3-Yl)-2-Methylpyrimidine Trifluoroacetate Salt; 4-(Azetidin-3-yl)-2-methylpyrimidine, TFA
EINECS	Contact for details

Quality Control

Our 4-(Azetidin-3-Yl)-2-Methylpyrimidine Tfa is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.