Description

4-(Azetidin-3-Yl)Pyrimidine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A versatile scaffold for the synthesis of novel drug candidates targeting a range of therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its azetidine-pyrimidine core.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients in crop protection products.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Ligand Development: Acts as a precursor for creating specialized ligands in catalysis and material science applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific heterocyclic frameworks.

Basic Information

Product Name	4-(Azetidin-3-Yl)Pyrimidine
CAS No.	1236861-79-2
Molecular Formula	C7H9N3
Molecular Weight	135.17 g/mol
Synonyms	4-(Azetidin-3-yl)pyrimidine; 3-Pyrimidin-4-ylazetidine; Azetidine, 3-(4-pyrimidinyl)-; Pyrimidine, 4-(3-azetidinyl)-; 4-(Azetidin-3-yl)pyrimidine hydrochloride (salt forms); 3-(Pyrimidin-4-yl)azetidine; 4-Azetidin-3-yl-pyrimidine
EINECS	Contact for details

Quality Control

Our 4-(Azetidin-3-Yl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.