Description

2(3H)-Benzoxazolone, 5-[[2-[(4-Fluoro-3-Methoxy-5-Methylphenyl)Amino]-5-Methyl-4-Pyrimidinyl]Amino]- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a key building block for novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting oncology, neurology, and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel small-molecule drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry R&D: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Development: A key component in the synthesis pathway of targeted cancer therapies due to its specific heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Biochemical Research: May be employed as a tool compound or probe in biochemical assays to study specific enzyme or receptor interactions.
• Fine Chemical Synthesis: Used in the production of other complex, high-value specialty chemicals for research purposes.

Basic Information

Product Name	2(3H)-Benzoxazolone, 5-[[2-[(4-Fluoro-3-Methoxy-5-Methylphenyl)Amino]-5-Methyl-4-Pyrimidinyl]Amino]-
CAS No.	1236667-40-5
Molecular Formula	C20H19FN6O3
Molecular Weight	410.40 g/mol
Synonyms	5-[[2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4-pyrimidinyl]amino]-2(3H)-benzoxazolone; 2(3H)-Benzoxazolone, 5-((2-((4-fluoro-3-methoxy-5-methylphenyl)amino)-5-methyl-4-pyrimidinyl)amino)-; 5-((2-((4-Fluoro-3-methoxy-5-methylphenyl)amino)-5-methylpyrimidin-4-yl)amino)benzo[d]oxazol-2(3H)-one; CAS 1236667-40-5; 2-Benzoxazolinone derivative; Fluoromethoxymethyl anilinopyrimidinyl benzoxazolone.
EINECS	Contact for details

Quality Control

Our 2(3H)-Benzoxazolone, 5-[[2-[(4-Fluoro-3-Methoxy-5-Methylphenyl)Amino]-5-Methyl-4-Pyrimidinyl]Amino]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.