Description

Ethyl 7-[(E)-2-(Dimethylamino)Vinyl]-2-(Trifluoromethyl)-[1,2,4]Triazolo[1,5-A]Pyrimidine-6-Carboxylate is a high-value, functionalized heterocyclic compound designed for advanced chemical synthesis. This molecule is significant for its unique structural features, including a triazolopyrimidine core, a trifluoromethyl group for enhanced lipophilicity and metabolic stability, and a reactive vinyl-dimethylamino moiety, making it a versatile building block. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Serves as a sophisticated building block for developing new herbicides, fungicides, and insecticides with potentially improved efficacy and environmental profiles.
• Chemical Biology Probe Development: Used to create tool compounds for studying biological pathways and target validation due to its modifiable functional groups.
• Material Science Precursor: Potential use in synthesizing specialty polymers or organic electronic materials that require complex, nitrogen-rich heterocycles.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic projects.

Basic Information

Item	Details
Product Name	Ethyl 7-[(E)-2-(Dimethylamino)Vinyl]-2-(Trifluoromethyl)-[1,2,4]Triazolo[1,5-A]Pyrimidine-6-Carboxylate
CAS No.	1235515-23-7
Molecular Formula	C15H16F3N5O2
Molecular Weight	355.32 g/mol
Synonyms	Ethyl 7-[(E)-2-(dimethylamino)ethenyl]-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate; 7-[(E)-2-(Dimethylamino)vinyl]-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester; 1235515-23-7; 2-(Trifluoromethyl)-7-[(E)-2-(dimethylamino)vinyl][1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester; [1,2,4]Triazolo[1,5-a]pyrimidine-6-carboxylic acid, 7-[(E)-2-(dimethylamino)ethenyl]-2-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 7-[(E)-2-(Dimethylamino)Vinyl]-2-(Trifluoromethyl)-[1,2,4]Triazolo[1,5-A]Pyrimidine-6-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.