Description

2-Pyrimidinamine,4-Methyl-n-[5-Methyl-4-(1H-Pyrazol-4-Yl)-2-Thiazolyl]- is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially within oncology and antiviral research domains.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic molecules.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the development of protein kinase inhibitors for oncology applications.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying enzyme function and cellular signaling.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	2-Pyrimidinamine,4-Methyl-n-[5-Methyl-4-(1H-Pyrazol-4-Yl)-2-Thiazolyl]-
CAS No.	1235318-89-4
Molecular Formula	C12H12N6S
Molecular Weight	272.33 g/mol
Synonyms	4-Methyl-N-[5-methyl-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-yl]pyrimidin-2-amine; 4-Methyl-N-(5-methyl-4-(1H-pyrazol-4-yl)thiazol-2-yl)pyrimidin-2-amine; 2-Pyrimidinamine, 4-methyl-N-[5-methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-; 4-Methyl-2-((5-methyl-4-(1H-pyrazol-4-yl)thiazol-2-yl)amino)pyrimidine; CAS 1235318-89-4
EINECS	Contact for details

Quality Control

Our production of 2-Pyrimidinamine,4-Methyl-n-[5-Methyl-4-(1H-Pyrazol-4-Yl)-2-Thiazolyl]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized and released according to in-house specifications developed for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.